Medical Science Syllabus UPSC Mains

Medical Science Syllabus Paper – I

Human Anatomy

• Applied anatomy including blood and nerve supply of upper and lower limbs and joints of shoulder, hip and knee.
• Gross anatomy, blood supply and lymphatic drainage of tongue, thyroid, mammary gland, stomach, liver, prostate, gonads and uterus
• Applied anatomy of diaphragm, perineum and inguinal region.
• Clinical anatomy of kidney, urinary bladder, uterine tubes, vas deferens.
• Embryology→ Placenta and placental barrier. Development of heart, gut, kidney, uterus, ovary, testis and their common congenital abnormalities.
• Central and peripheral autonomic nervous system→ Gross and clinical anatomy of ventricles of brain, circulation of cerebrospinal fluid; Neural pathways and lesions of cutaneous sensations, hearing and vision; Cranial nerves, distribution and clinical significance; Components of autonomic nervous system.

Human Physiology

• Conduction and transmission of impulse, mechanism of contraction, neuromuscular transmission, reflexes, control of equilibrium, posture and muscle tone, descending pathways, functions of cerebellum, basal ganglia, Physiology of sleep and consciousness.
• Endocrine system→ Mechanism of action of hormones, formation, secretion, transport, metabolism, function and regulation of secretion of pancreas and pituitary gland.
• Physiology of reproductive system→ menstrual cycle, lactation, pregnancy.
• Blood→ Development, regulation and fate of blood cells.
• Cardio-vascular, cardiac output, blood pressure, regulation of cardiovascular functions;

Biochemistry

• Organ function tests-liver, kidney, thyroid
• Protein synthesis.
• Vitamins and minerals.
• Restriction fragment length polymorphism (RFLP).
• Polymerase chain reaction (PCR).
• Radio – immunoassays (RIA).

Pathology

• Inflammation and repair, disturbances of growth and cancer, Pathogenesis and histopathology of rheumatic and ischemic heart disease and diabetes mellitus.
• Differentiation between benign, malignant, primary and metastatic malignancies, Pathogenesis and histopathology of bronchogenic carcinoma, carcinoma breast, oral cancer, cancer cervix, leukemia, Etiology, pathogenesis and histopathology of – cirrhosis liver, glomerulonephritis, tuberculosis, acute osteomyelitis.

Microbiology

• Humoral and cell mediated immunity
• Diseases caused by and laboratory diagnosis of –

• Meningococcus, Salmonella
• Shigella, Herpes, Dengue, Polio
• HIV/AIDS, Malaria, E. Histolytica, Giardia
• Candida, Cryptococcus, Aspergillus

Pharmacology

• Mechanism of action and side effects of the following drugs

• Antipyretics and analgesics, Antibiotics, Antimalaria; Antikala-azar,Antidiabetics
• Antihypertensive, Antidiuretics, General and cardiac vasodilators, Antiviral,
• Antiparasitic, Antifungal, Immunosuppressants, Anticancer

Forensic Medicine and Toxicology

• Forensic examination of injuries and wounds;
• Examination of blood and seminal stains; poisoning, sedative overdose, hanging, drowning, burns, DNA and finger print study

Medical Science Syllabus Paper – II

General Medicine

• Etiology, clinical features, diagnosis and principles of management (including prevention) of→ – Tetanus, Rabies, AIDS, Dengue, Kala-azar, Japanese Encephalitis.
• Etiology, clinical features, diagnosis and principles of management of –

• Ischaemic heart disease, pulmonary embolism
• Bronchial asthma
• Pleural effusion, tuberculosis, Malabsorption syndromes, acid peptic diseases, Viral hepatitis and cirrhosis of liver
• Glomerulonerphritis and pyelonephritis, renal failure, nephrotic syndrome, renovascular hypertension, complications of diabetes mellitus, coagulation disorders, leukemia, Hypo and hyper thyrodism, meningitis and encephalitis.
• Imaging in medical problems, ultrasound, echocardiogram, CT scan, MRI.
• Anxiety and Depressive Psychosis and schizophrenia and ECT.

Pediatrics

• Immunization, Baby friendly hospital, congenital cyanotic heart disease, respiratory distress syndrome, broncho – pneumonias, kernicterus.
• IMNCI classification and management, PEM grading and management.
• ARI and Diarrhea of under five and their management.

Dermatology

• Psoriasis, Allergic dermatitis, scabies, eczema, vitiligo, Stevan Johnson’s syndrome, Lichen Planus.

General Surgery

• Clinical features, causes, diagnosis and principles of management of cleft palate, harelip.
• Laryngeal tumor, oral and esophageal tumors.
• Peripheral arterial diseases, varicose veins, coarctation of aorta
• Tumors of Thyroid, Adrenal Glands
• Abscess, cancer, fibroadenoma and adenosis of breast.
• Bleeding peptic ulcer, tuberculosis of bowel, ulcerative colitis, cancer stomach.
• Renal mass,cancer Prostate..
• Haemothorax, stones of Gall bladder, Kidney, Ureter and Urinary Bladder.
• Management of surgical conditions of Rectum, Anus and Anal canal, Gall bladder and Bile ducts
• Splenomegaly, cholecystitis, portal hypertension, liver abscess, peritonitis, carcinoma head of pancreas.
• Fractures of spine, Colles’ fracture and bone tumors.
• Endoscopy
• Laprascopic Surgery.

Obstetrics and Gynaecology including Family Planning

• Diagnosis of pregnancy
• Labour management, complications of 3rd stage, Antepartum and postpartum hemorrhage, resuscitation of the newborn, Management of abnormal lie and difficult labour, Management of small for date or premature newborn.
• Diagnosis and management of anemia. Preeclampsia and Toxaemias of pregnancy, Management of Post menopausal Syndrome.
• Intra-uterine devices, pills, tubectomy and vasectomy. Medical termination of pregnancy including legal aspects.
• Cancer cervix.
• Leucorrhoea, pelvic pain, infertility, dysfunctional uterine bleeding (DUB), amenorrhoea, Fibroid and prolapse of uterus.

Community Medicine (Preventive and Social Medicine)

• Principles, methods, approach and measurements of Epidemiology
• Nutrition, nutritional diseases / disorders & Nutrition Programmes.
• Health information Collection, Analysis and Presentation.
• Objectives, components and critical analysis of National programmes for control/eradication of –

• Malaria, Kala-azar, Filaria and Tuberculosis,
• HIV/AIDS, STDs and Dengue
• Critical appraisal of Health care delivery system
• Health management and administration → Techniques, Tools, Programme Implementation and Evaluation
• Objective, Component, Goals and Status of Reproductive and Child Health, National Rural Health Mission and Millennium Development Goals
• Management of hospital and industrial waste